Imprinting And Early Exposure To Developed International Markets: The Case Of The New Multinationals

Working Papers

Previous research has analyzed the imprinting effect associated with the firm’s international expansion without considering the full range of differences between home and host countries. These differences are important because, depending on the development gap, and the direction of the difference, learning opportunities and the possibility of upgrading firm’s capabilities will be vastly different. Read More

Welfare Effects of Physician-Industry Interactions: Evidence from Patent Expiration

Working Papers

Many transactions occur via expert advisors, especially in the healthcare sector, and as such, firms frequently implement strategies to influence these advisors. The efficiency of these interactions is an empirical question. Read More

Standard vs. Partnership-Embedded Licensing: Attention and the Relationship Between Licensing and Product Innovations

Published Research

This paper examines the relationship between the licensing of knowledge and the creation of product innovations. We consider that firms organize licensing activities in different ways and that licensees are heterogeneous with respect to the attention available to apply and transform in-licensed knowledge to create new product innovations. Read More

From Invention to Innovation: A Multi-Study Investigation of Firm Strategy and Outcomes in Clinical Trials

Funded Research Proposal

The translation of invention to innovation is a topic that has received significant research attention in recent times. Scholars have recognized that our understanding of the factors that shape whether and when innovative technologies arise and transform industries cannot be complete without comprehending how scientific or technological discovery evolves into commercial adoption. Read More

Building a Connected Strategy: From Customer Experience to Technology Platforms

Connected Strategy Conference

At the Mack Institute’s Fall Conference 2016, leaders from across industries discussed their companies’ pursuit of “connected strategy” defined by continuous customer engagement.Read More

Innovation and the Evolution of Industries: History-Friendly Models

Published Research

The disruptive impacts of technological innovation on established industrial structures has been one of the distinguishing features of modern capitalism. In this book, four leading figures in the field of Schumpeterian and evolutionary economic theory draw on decades of research to offer a new, ‘history-friendly’ perspective on the process of creative destruction.Read More

Business Model Innovation: How Far Beyond the Pill?

Funded Research Proposal

A central feature of the strategic growth-seeking discipline is full-spectrum innovation; the systematic search for growth opportunities by rethinking and reimaging the value proposition and business model components of the strategy. The purpose of this research project is to continue the Mack Institute sponsored research on business model innovation in the pharmaceutical industry.Read More

Decoding the Adaptability-Rigidity Puzzle: Evidence from Pharmaceutical Incumbents’ Pursuit of Gene Therapy and Monoclonal Antibodies

Published Research

The emergence of radical technologies presents a significant challenge to incumbent firms. We study firms’ management of radical technological change by separating their actions into upstream research (“R” of R&D) and downstream development (“D” of R&D).Read More

Opening Up but Staying Local: Insights from Partnership Formations between Established and Startup Firms

Working Papers

In this paper, we develop a theoretical framework that considers that firms may be subject to both spatial and temporal myopia when crossing organizational boundaries and have a history of failures and successes in solving R&D problems. We use this framework to clarify how established firms search for and select among emerging partnering opportunities.Read More

Origins and Outcomes of Entrepreneurs’ Network Ties

Published Research

This research explores the relationship between incumbent pharmaceutical firms and biotechnology startups. Skilled incumbents are more likely to bring a drug to market, market the drug well, etc., and add value to the startup and increase its chance of a successful exit (IPO or M&A event).Read More

Portfolio Management in New Drug Development

Published Research

The pharmaceutical industry leads all industries in terms of R&D spend. Portfolio management in new drug development is extremely challenging due to long drug development cycles and high probabilities of failure.Read More