What Wharton MBAs Can Teach Penn Scientists

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Every year, university researchers make discoveries that could change the way we treat disease, power our communities, or improve the technologies we rely on every day. But promising discoveries don’t always make it out of the lab.  A researcher may have years of validated data behind an invention and still have noRead More

Collaborative Innovation Program Spotlight: Agentic AI for Supply Chain Strategy

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For Hasan Pasha WEMBA’26, the Mack Institute’s Collaborative Innovation Program (CIP) offered a chance to apply classroom ideas to a real business challenge. The experiential learning course pairs Wharton students with corporate partners to tackle complex problems and develop innovation strategies.  Pasha entered Wharton after more than two decades working across consulting, hardware product design,Read More

Innovation in Sports Fan Engagement

Baseball player in striped uniform holding a bat, ready to swing, with a large stadium in the background. The image has a blue overlay. Innovation in Sports Fan Engagement Spring 2026 Conference Report Digital transformation has expanded the ways fans engage with sports, creating new opportunities for personalization, global reach, and interactive experiences. At the same time, it has introduced fragmentation. Fans now follow teams and leagues across multiple platforms and streaming services, oftenRead More

Research Spotlight: Hamsa Bastani and Angel Tsai-Hsuan Chung On More Effective Classroom AI

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For many students, asking ChatGPT for homework help has replaced raising a hand in class or going to office hours. As AI becomes a default classroom tutor, educators are grappling with a new question: how do you design these tools so they actually support learning?  A new paper from Angel Tsai-Hsuan Chung (Wharton, PhDRead More

New White Paper: Can AI Manage an Entire Medical Decision Process?

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Artificial intelligence has already proven it can perform specific medical tasks, such as interpreting X-rays or flagging risks in patient data. But caring for patients is not a series of isolated decisions. It is a dynamic process that unfolds over time, requiring clinicians to interpret signals from multiple sources andRead More

Digital Twins 2.0: Making the Invisible Visible

Futuristic digital illustration of two human profiles, facing each other, composed of glowing lines and dots, symbolizing artificial intelligence and connectivity. Digital Twins 2.0: Making the Invisible Visible  Fall 2025 Conference Report Digital twins are moving rapidly from niche technology to a central tool for business innovation. From factory floors and operating rooms to autonomous vehicles and global enterprises, the technology is shifting from experimental pilots to scalable, revenue-generating systems. TheRead More

Y-Prize 2025-26 Finalists Announced

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Congratulations to the four student teams chosen as finalists for this year’s Y-Prize competition: Aeronyx, Carbo Wells, Haven and Lattica! The Y-Prize competition challenges students to build their entrepreneurial skills by creating business plans for technologies invented at Penn Engineering. The team with the best commercial application wins $15,000 to helpRead More

Insights from Prof. Tyler Wry: Creating Value Beyond the Bottom Line

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On Tuesday, November 19, the Mack Institute co-hosted, along with Pennovation Works and the Penn Center for Innovation, the semester’s first installment of the Entrepreneurship Speaker Series featuring Wharton Professor Tyler Wry. His presentation, “Brace for Impact: Value Creation Beyond the Bottom Line,” explored how businesses can pursue a “hybridRead More

Designers, Dentists, and MBAs: Building a New Model for University Innovation

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Many of today’s most transformative technologies have their origins in university research, from life-saving drugs and medical devices to advanced building materials. When these discoveries succeed in the marketplace, they not only improve lives but also become an important source of revenue for universities.  But the path from lab toRead More

Disrupting the Life Sciences Commercial Model: Exploring the Future Impact of AI and Patient-Centric Healthcare

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On Friday, September 26, the Mack Institute, in partnership with EVERSANA, AWS and Modus Create, hosted Disrupting the Life Sciences Commercial Model: Exploring the Future Impact of AI and Patient-Centric Healthcare. This intimate event brought together senior executives from pharma and medtech with Wharton and Penn faculty to explore how AI,Read More

New Report: Generative AI Adoption in the U.S. Military

Stylized depiction of the American flag with glowing red stripes and star patterns against a dark, mountainous landscape. The U.S. Department of Defense is one of the most complex organizations in the world — so how is it approaching generative AI? A new report from Wharton’s Prof. Serguei Netessine and WG’25 Andrew Stiles examines the DoD’s early steps toward integrating GenAI and highlights lessons that industry leaders canRead More

Mack Institute Pilots New MBA Course, Commercialization of Academic Science

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The Mack Institute is pleased to announce a new course for MBA students, Commercialization of Academic Science, piloting in Fall 2025. This hands-on course pairs student teams with Penn researchers who are developing cutting-edge technologies across healthcare, robotics, artificial intelligence, and more. Students will be tasked with conducting customer discovery,Read More

Research Spotlight: David Hsu on Sidestepping the Startup Integration Trap

A person in a suit standing in a bright office environment with large windows. Startup acquisitions by established firms are becoming more common, especially in fast-moving industries like tech and healthcare. But integrating a newly-acquired startup presents challenges, and can end up quashing creativity and worsening innovation outcomes. A new study, funded in part by the Mack Institute and conducted by Mack Core TeamRead More