In this paper, we propose combining data from both surrogate and true outcomes to improve decision-making within a late-phase clinical trial.…Read More
Adaptive Clinical Trial Designs With Surrogates: When Should We Bother?
decision-making
The Impact of Acquisitions on Clinical Decisions: Evidence from Physician Practice Management Companies
Mergers and acquisitions are rapidly transforming the organization of physician services in the United States, raising concerns over the cost and the quality of health care. This paper studies how medical practice acquisitions by Physician Practice Management Companies (PPMCs) impact physician behavior and patient health.…Read More
Building a More Intelligent Enterprise
Businesses must develop a sustainable competitive edge in order to succeed in the long run. One way to achieve this is by leveraging technology-enabled insights with a sophisticated understanding of decision making, judgment, and reasoning to make smarter decisions in the face of uncertainty.…Read More
Preferences, Structure and Influence: The Engineering of Consent
I present a decision process framework that informs the design and implementation of stakeholder influence strategy. This process combines insights from agent-based dynamic utility and dynamic network processes. Stakeholders strategically seek an outcome as close as possible to their preferred point but also wish to be on the winning side and not to pursue positions divergent from stakeholders with whom they have strong affective ties.…Read More
A Theory of the Emergence of Organizational Form: The Dynamics of Cross-border Knowledge Production by Indian Firms
This paper uses a complex systems perspective to develop a theory of how human interaction dynamics (HID)-strategic decision processes and organizational mechanisms-for knowledge production under uncertainty give rise to a new organizational form. Our theoretical framework is derived from an inductive study of the international expansion of 14 Indian biotechnology and software firms.…Read More
Habit, Deliberation and Action: Strengthening the Microfoundations of Routines and Capabilities
The proponents of the “microfoundations project” have advanced a number of criticisms of theories of organizational routines and capabilities. While the criticisms derive in part from philosophical or methodological premises that are open to serious question, and tend to ignore the empirical research on the subject, there remains a valid core concern about the foundational characterization of human nature.…Read More
Falling Flat: Failed Technologies and Investment Under Uncertainty
This study theorizes about the behavioral and knowledge creation implications of betting on the losing technology in a competing technology situation and focuses on three main outcomes. First, in a situation with competing technological options, firms that invest initially in the losing technology will be less successful subsequently in building new knowledge.…Read More
Perspectives on Firm Decision Making During Risky Technology Acquisitions
A novel survey dataset on computed tomography (CT) machine acquisition is used to explore which theories best answer two questions from the decision making literature. First, what determines how much uncertainty a firm has when investing in updated technology? Second, what determines the value of the acquisition? In answering these questions, two theoretical comparisons are conducted.…Read More