Challenges in the Gene Therapy Commercial Ecosystem

Published Research

The emergence of biotech has resulted in a rich ecosystem of different types of actors contributing to the technological advance. Despite the enormous promise of biotech-based therapeutics, there is substantial uncertainty regarding when scientific discoveries will emerge, whether these discoveries will achieve clinical success, and how commercialized treatments will create value. Read More

Achieving Sustainability: Insights from Biogas Ecosystems in India

Published Research

This paper focuses on how the use of renewable energy technologies such as biogas can help to achieve environmental and socio-economic sustainability. It combines research on sustainable consumption and production, natural and industrial ecosystems and renewable energy adoption. Read More

Corporate VCs Yield Better Innovation Outcomes

Recent research by Senior Fellow Gary Dushnitsky measures the innovation success of new biotech ventures by tracking their patenting and publishing rates. He and coauthor Elisa Alvarez-Garrido find that the identity of the investor makes a big difference.Read More

R&D Production Team Composition and Firm-Level Innovation

Working Papers

How should a firm organize the diversity of technical experience contained within its pool of inventive human capital when firm-level innovation is a desired performance outcome? Using a sample of biotechnology start-ups observed from their founding onwards we examine the implications of alternate firm-level design regimes.Read More

Origins and Outcomes of Entrepreneurs’ Network Ties

Published Research

This research explores the relationship between incumbent pharmaceutical firms and biotechnology startups. Skilled incumbents are more likely to bring a drug to market, market the drug well, etc., and add value to the startup and increase its chance of a successful exit (IPO or M&A event).Read More

Knowledge Brokering and Organizational Innovation: Founder Imprinting Effects

Published Research

We empirically examine the innovation consequences of organizational knowledge brokering, the ability to effectively apply knowledge from one technical domain to innovate in another. We investigate how organizational innovation outcomes vary by founders’ initial mode of venture ideation.Read More

Publications and Patents in Corporate Venture–Backed Biotech

Published Research

Biotech startups increasingly turn to corporate venture capital (VC) arms for funding, rather than to traditional venture capitalists. The innovation implications for these startups remain unexplored. Here, we present evidence that the shift in funding patterns is associated with a greater output of scientific publications as well as patenting.Read More

Venture Performance, VC Experience, and Global Financial Markets

Working Papers

Even though it is well understood that the success of entrepreneurial ventures depends to a great extent on their interorganizational relationships, the role of the external environment in which these relationships unfold remains relatively unexplored. In contrast, resource-dependence theory regards the environment as a major factor in the degree to which external resources contribute to firm performance.Read More

Corporate-Backed Biotech Startups: Exploring the Innovation Implications

Working Papers

Biotech startups increasingly turn to Corporate VC arms for capital, rather than financially-oriented VCs. The innovation implications for these startups remain unexplored. We present evidence that the shift in funding patterns is associated with greater academic publications as well as patenting output.Read More